Screen-detected lobular carcinoma in situ (LCIS) of the breast: 166 cases within the National Health Service Breast Screening Programme (NHSBSP)
نویسندگان
چکیده
منابع مشابه
Identification of women at high genetic risk of breast cancer through the National Health Service Breast Screening Programme (NHSBSP).
Breast cancer is a multifactorial disease with an inherited predisposition being implicated in around 5% of all cases. Using previous epidemiological data assessing risks for the relatives of women with breast cancer, we have identified 154 women (from a screened population of 35,505) and 289 of their relatives between 50 and 64 years who have more than twice the age related risk of developing ...
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Bilateral risk reducing mastectomy results in the greatest breast cancer risk reduction but is an irreversible intervention. Total mastectomy can never remove all breast tissue and there is always a small risk of breast cancer. Regular follow up and surveillance is beneficial. We present the case of a 47-year-old woman who presented with axillary lymph node metastatic breast cancer after risk r...
متن کاملLobular carcinoma in situ (LCIS) of the breast: is long-term outcome similar to ductal carcinoma in situ (DCIS)? Analysis of 200 cases
BACKGROUND Lobular carcinomas in situ (LCIS) represent 1-2% of all breast cancers. Both significance and treatment remain widely debated, as well as the possible similarities with DCIS. MATERIALS AND METHODS Two hundred patients with pure LCIS were retrospectively analyzed in seven centres from 1990 to 2008. Median age was 52 years; 176 patients underwent breast-conserving surgery (BCS) and 2...
متن کاملThe management of lobular carcinoma in situ (LCIS). Is LCIS the same as ductal carcinoma in situ (DCIS)?
Lobular carcinoma in situ was first described over 60 years ago. Despite the long history, it continues to pose significant difficulties in screening, diagnosis, management and treatment. This is partly due its multi-focal and bilateral presentation, an incomplete understanding of its biology and natural history and perpetuation of misconceptions gathered over the last decades. In this review, ...
متن کاملCarcinoma of the Breast, the National Screening Programme
Broadly speaking we are in a mess over breast carcinoma. It has always been so and anyone industrious enough to study the literature in depth will have realised it. Despite the past twenty years of frenetic investigation, therapeutic revolution and comprehensive trials, the end results are not improved. Perhaps the only time when I recall that the whole enterprise was seemingly well appreciated...
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ژورنال
عنوان ژورنال: Breast Cancer Research
سال: 2004
ISSN: 1465-542X
DOI: 10.1186/bcr839